Ablative therapies for lung metastases: a need to acknowledge the efficacy and toxicity of stereotactic ablative body radiotherapy

Stereotactic ablative body radiotherapy for lung cancer.

Lung stereotactic ablative radiotherapy (SABR) is a method of delivering high 'ablative' doses of radiotherapy to tumours in the lung. It was developed at the Karolinska Institute in the early 1990s using the methods established in cranial radiosurgery with multiple beams prescribed to an isodose and using a custom designed stereotactic body frame for immobilisation. Since then, aligned with th...

Stereotactic ablative radiotherapy for lung cancer

Stereotactic ablative radiotherapy (SABR), which is also referred to as stereotactic body radiotherapy (SBRT), is defined as “the precise irradiation of an image defined extra-cranial lesion associated with the use of high radiation dose in a small number of fractions”. SABR is a relatively recent advance in the treatment of small peripheral non-small cell lung tumours. The concept of SABR was ...

Clinical efficacy of stereotactic ablative radiotherapy for lung metastases arising from colorectal cancer

BACKGROUND Limited data describe the prognosis after stereotactic ablative radiotherapy for lung metastases arising from colorectal cancer. Thus, we evaluated treatment outcomes of stereotactic ablative radiotherapy for those patients. METHODS The study involved patients received stereotactic ablative radiotherapy for one to three lung metastases arising from colorectal cancer at a single ins...

Stereotactic ablative body radiotherapy for hepatocellular carcinoma or cholangiocarcinoma

Prostate stereotactic ablative body radiotherapy using a standard linear accelerator: toxicity, biochemical, and pathological outcomes.

BACKGROUND AND PURPOSE Biological dose escalation through stereotactic ablative radiotherapy (SABR) holds promise of improved patient convenience, system capacity and tumor control with decreased cost and side effects. The objectives are to report the toxicities, biochemical and pathologic outcomes of this prospective study. MATERIALS AND METHODS A phase I/II study was performed where low ris...